AKR1C1 anticorps (AA 1-323)

N° du produit ABIN514921

Cet anticorps Souris Polyclonal détecte spécifiquement AKR1C1 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour AKR1C1 anticorps (AA 1-323) (ABIN514921)

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AKR1C1 anticorps

Épitope: AA 1-323

Fonction: Mouse polyclonal antibody raised against a full-length human AKR1C1 protein.

Séquence: MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA VEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: AKR1C1 (NP_001344.2, 1 a.a. ~ 323 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-AKR1C1 (ABIN514921)

Han, Bourboulia, Jensen-Taubman, Isaac, Wei, Stetler-Stevenson: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." dans: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).

Choi, Ryoo, Kang, Kwak: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." dans: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." dans: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Détails sur AKR1C1

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Autre désignation: AKR1C1

Sujet: Full Gene Name: aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1, 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
Synonyms: 2-ALPHA-HSD,20-ALPHA-HSD,C9,DD1,DDH,DDH1,H-37,HAKRC,MBAB,MGC8954

ID gène: 1645

NCBI Accession: NM_001353

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process