RNF8 anticorps (AA 1-485)

N° du produit ABIN522468

Détail du produit anti-RNF8 anticorps

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Épitope: AA 1-485

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: Mouse polyclonal antibody raised against a full-length human RNF8 protein.

Séquence: MGEPGFFVTG DRAGGRSWCL RRVGMSAGWL LLEDGCEVTV GRGFGVTYQL VSKICPLMIS RNHCVLKQNP EGQWTIMDNK SLNGVWLNRA RLEPLRVYSI HQGDYIQLGV PLENKENAEY EYEVTEEDWE TIYPCLSPKN DQMIEKNKEL RTKRKFSLDE LAGPGAEGPS NLKSKINKVS CESGQPVKSQ GKGEVASTPS DNLDPKLTAL EPSKTTGAPI YPGFPKVTEV HHEQKASNSS ASQRSLQMFK VTMSRILRLK IQMQEKHEAV MNVKKQTQKG NSKKVVQMEQ ELQDLQSQLC AEQAQQQARV EQLEKTFQEE EQHLQGLEIA QGEKDLKQQL AQALQEHWAL MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE LQCIICSEYF IEAVTLNCAH SFCSYCINEW MKRKIECPIC RKDIKSKTYS LVLDNCINKM VNNLSSEVKE RRIVLIRERK AKRLF

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: RNF8 (NP_003949.1, 1 a.a. ~ 485 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RNF8 (ABIN522468)

Hodge, Ismail, Edwards, Hura, Xiao, Tainer, Hendzel, Glover: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." dans: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).

Yang, Deng, Hau, Liu, Lau, Cheung, Huen, Tsao: "Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 8, pp. 937-50, (2015) (PubMed).

Hau, Deng, Jia, Yang, Tsurumi, Chiang, Huen, Tsao: "Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells." dans: Journal of virology, Vol. 89, Issue 1, pp. 652-68, (2014) (PubMed).

Morris, Boutell, Keppler, Densham, Weekes, Alamshah, Butler, Galanty, Pangon, Kiuchi, Ng, Solomon: "The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress." dans: Nature, Vol. 462, Issue 7275, pp. 886-90, (2009) (PubMed).

Détails sur RNF8

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Autre désignation: RNF8 (RNF8 Produits)

Sujet: Full Gene Name: ring finger protein 8
Synonyms: FLJ12013,KIAA0646

ID gène: 9025

NCBI Accession: NM_003958

Pathways: Production of Molecular Mediator of Immune Response