B3GAT3 anticorps (AA 1-335)

N° du produit ABIN525639

Détail du produit anti-B3GAT3 anticorps

Antigène: B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))

Épitope: AA 1-335

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp B3GAT3 est non-conjugé

Application: Western Blotting (WB)

Fonction: Mouse polyclonal antibody raised against a full-length human B3GAT3 protein.

Séquence: MKLKLKNVFL AYFLVSIAGL LYALVQLGQP CDCLPPLRAA AEQLRQKDLR ISQLQAELRR PPPAPAQPPE PEALPTIYVV TPTYARLVQK AELVRLSQTL SLVPRLHWLL VEDAEGPTPL VSGLLAASGL LFTHLVVLTP KAQRLREGEP GWVHPRGVEQ RNKALDWLRG RGGAVGGEKD PPPPGTQGVV YFADDDNTYS RELFEEMRWT RGVSVWPVGL VGGLRFEGPQ VQDGRVVGFH TAWEPSRPFP VDMAGFAVAL PLLLDKPNAQ FDSTAPRGHL ESSLLSHLVD PKDLEPRAAN CTRVLVWHTR TEKPKMKQEE QLQRQGRGSD PAIEV

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: B3GAT3 (NP_036332.2, 1 a.a. ~ 335 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-B3GAT3 (ABIN525639)

Job, Mizumoto, Smith, Couser, Brazil, Saal, Patterson, Gibson, Soden, Miller, Thiffault, Saunders, Yamada, Hoffmann, Sugahara, Farrow: "Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype." dans: BMC medical genetics, Vol. 17, Issue 1, pp. 86, (2016) (PubMed).

Budde, Mizumoto, Kogawa, Becker, Altmüller, Thiele, Rüschendorf, Toliat, Kaleschke, Hämmerle, Höhne, Sugahara, Nürnberg, Kennerknecht: "Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3." dans: Human genetics, Vol. 134, Issue 7, pp. 691-704, (2015) (PubMed).

Baasanjav, Al-Gazali, Hashiguchi, Mizumoto, Fischer, Horn, Seelow, Ali, Aziz, Langer, Saleh, Becker, Nürnberg, Cantagrel, Gleeson, Gomez, Michel, Stricker, Lindner, Nürnberg, Sugahara, Mundlos et al.: "Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. ..." dans: American journal of human genetics, Vol. 89, Issue 1, pp. 15-27, (2011) (PubMed).

Hiyama, Gajghate, Sakai, Mochida, Shapiro, Risbud: "Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc." dans: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9824-34, (2009) (PubMed).

Détails sur B3GAT3

Antigène: B3GAT3 (beta-1,3-Glucuronyltransferase 3 (Glucuronosyltransferase I) (B3GAT3))

Autre désignation: B3GAT3 (B3GAT3 Produits)

Synonymes: anticorps GLCATI, anticorps 2810405M13Rik, anticorps GlcUAT-I, anticorps Glcat-i, anticorps beta-1,3-glucuronyltransferase 3, anticorps beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I), anticorps B3GAT3, anticorps B3gat3

Sujet: Full Gene Name: beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
Synonyms: GLCATI,GlcAT-I

ID gène: 26229

NCBI Accession: NM_012200

Pathways: Glycosaminoglycan Metabolic Process