LARP6 anticorps (AA 1-491)

N° du produit ABIN527496

Cité dans 8 publications. Cet anticorps anti-LARP6 Polyclonal Souris (ABIN527496) détecte spécifiquement LARP6 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour LARP6 anticorps (AA 1-491) (ABIN527496)

Antigène: LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp LARP6 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-LARP6 anticorps

Épitope: AA 1-491

Fonction: Mouse polyclonal antibody raised against a full-length human LARP6 protein.

Séquence: MAQSGGEARP GPKTAVQIRV AIQEAEDVDE LEDEEEGAET RGAGDPARYL SPGWGSASEE EPSRGHSGTT ASGGENERED LEQEWKPPDE ELIKKLVDQI EFYFSDENLE KDAFLLKHVR RNKLGYVSVK LLTSFKKVKH LTRDWRTTAH ALKYSVVLEL NEDHRKVRRT TPVPLFPNEN LPSKMLLVYD LYLSPKLWAL ATPQKNGRVQ EKVMEHLLKL FGTFGVISSV RILKPGRELP PDIRRISSRY SQVGTQECAI VEFEEVEAAI KAHEFMITES QGKENMKAVL IGMKPPKKKP AKDKNHDEEP TASIHLNKSL NKRVEELQYM GDESSANSSS DPESNPTSPM AGRRHAATNK LSPSGHQNLF LSPNASPCTS PWSSPLAQRK GVSRKSPLAE EGRLNCSTSP EIFRKCMDYS SDSSVTPSGS PWVRRRRQAE MGTQEKSPGT SPLLSRKMQT ADGLPVGVLR LPRGPDNTRG FHGHERSRAC V

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: LARP6 (NP_060827, 1 a.a. ~ 491 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-LARP6 (ABIN527496)

Blackstock, Higashi, Sukhanov, Shai, Stefanovic, Tabony, Yoshida, Delafontaine: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." dans: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).

Wang, Stefanovic: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." dans: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).

Manojlovic, Blackmon, Stefanovic: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." dans: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).

Vukmirovic, Manojlovic, Stefanovic: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." dans: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).

Manojlovic, Stefanovic: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." dans: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).

Challa, Stefanovic: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." dans: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).

Cai, Fritz, Stefanovic, Stefanovic: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." dans: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).

Cai, Fritz, Stefanovic, Stefanovic: "Nonmuscle myosin-dependent synthesis of type I collagen." dans: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).

Détails sur LARP6

Antigène: LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))

Autre désignation: LARP6

Sujet: Full Gene Name: La ribonucleoprotein domain family, member 6
Synonyms: ACHN,FLJ11196

ID gène: 55323

NCBI Accession: NM_018357