LEPRE1 anticorps (AA 1-390)

N° du produit ABIN528557

L’anticorps Souris Polyclonal anti-LEPRE1 a été validé pour WB. Il convient pour détecter LEPRE1 dans des échantillons de Humain. Il y a 9+ publications disponibles.

Aperçu rapide pour LEPRE1 anticorps (AA 1-390) (ABIN528557)

Antigène: LEPRE1 (Leucine Proline-Enriched Proteoglycan (Leprecan) 1 (LEPRE1))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp LEPRE1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LEPRE1 anticorps

Épitope: AA 1-390

Fonction: Mouse polyclonal antibody raised against a full-length human LEPRE1 protein.

Séquence: MLGEEHTRSI GPRESAKEYR QRSLLEKELL FFAYDVFGIP FVDPDSWTPE EVIPKRLQEK QKSERETAVR ISQEIGNLMK EIETLVEEKT KESLDVSRLT REGGPLLYEG ISLTMNSKLL NGSQRVVMDG VISDHECQEL QRLTNVAATS GDGYRGQTSP HTPNEKFYGV TVFKALKLGQ EGKVPLQSAH LYYNVTEKVR RIMESYFRLD TPLYFSYSHL VCRTAIEEVQ AERKDDSHPV HVDNCILNAE TLVCVKEPPA YTFRDYSAIL YLNGDFDGGN FYFTELDAKT VTAEVQPQCG RAVGFSSGTE NPHGVKAVTR GQRCAIALWF TLDPRHSERD RVQADDLVKM LFSPEEMDLS QEQPLDAQQG PPEPAQESLS GSESKPKDEL

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: LEPRE1 (AAH15309, 1 a.a. ~ 390 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-LEPRE1 (ABIN528557)

Huang, Mei, Lv, Li, Zhang, Pan, Tan, Guo, Luo, Chen, Liang, Wu: "Targeted exome sequencing identifies novel compound heterozygous mutations in P3H1 in a fetus with osteogenesis imperfecta type VIII." dans: Clinica chimica acta; international journal of clinical chemistry, Vol. 464, pp. 170-175, (2016) (PubMed).

Cabral, Perdivara, Weis, Terajima, Blissett, Chang, Perosky, Makareeva, Mertz, Leikin, Tomer, Kozloff, Eyre, Yamauchi, Marini: "Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta." dans: PLoS genetics, Vol. 10, Issue 6, pp. e1004465, (2014) (PubMed).

Takagi, Ishii, Barnes, Weis, Amano, Tanaka, Fukuzawa, Nishimura, Eyre, Marini, Hasegawa: "A novel mutation in LEPRE1 that eliminates only the KDEL ER- retrieval sequence causes non-lethal osteogenesis imperfecta." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36809, (2012) (PubMed).

Pyott, Schwarze, Christiansen, Pepin, Leistritz, Dineen, Harris, Burton, Angle, Kim, Sussman, Weis, Eyre, Russell, McCarthy, Steiner, Byers: "Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes." dans: Human molecular genetics, Vol. 20, Issue 8, pp. 1595-609, (2011) (PubMed).

Amor, Rauch, Gruenwald, Weis, Eyre, Roughley, Glorieux, Morello: "Severe osteogenesis imperfecta caused by a small in-frame deletion in CRTAP." dans: American journal of medical genetics. Part A, Vol. 155A, Issue 11, pp. 2865-70, (2011) (PubMed).

Baldridge, Lennington, Weis, Homan, Jiang, Munivez, Keene, Hogue, Pyott, Byers, Krakow, Cohn, Eyre, Lee, Morello: "Generalized connective tissue disease in Crtap-/- mouse." dans: PLoS ONE, Vol. 5, Issue 5, pp. e10560, (2010) (PubMed).

Willaert, Malfait, Symoens, Gevaert, Kayserili, Megarbane, Mortier, Leroy, Coucke, De Paepe: "Recessive osteogenesis imperfecta caused by LEPRE1 mutations: clinical documentation and identification of the splice form responsible for prolyl 3-hydroxylation." dans: Journal of medical genetics, Vol. 46, Issue 4, pp. 233-41, (2009) (PubMed).

van Dijk, Nesbitt, Zwikstra, Nikkels, Piersma, Fratantoni, Jimenez, Huizer, Morsman, Cobben, van Roij, Elting, Verbeke, Wijnaendts, Shaw, Högler, McKeown, Sistermans, Dalton, Meijers-Heijboer, Pals: "PPIB mutations cause severe osteogenesis imperfecta." dans: American journal of human genetics, Vol. 85, Issue 4, pp. 521-7, (2009) (PubMed).

Chang, Barnes, Cabral, Bodurtha, Marini: "Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex." dans: Human molecular genetics, Vol. 19, Issue 2, pp. 223-34, (2009) (PubMed).

Détails sur LEPRE1

Antigène: LEPRE1 (Leucine Proline-Enriched Proteoglycan (Leprecan) 1 (LEPRE1))

Autre désignation: LEPRE1

Sujet: Full Gene Name: leucine proline-enriched proteoglycan (leprecan) 1
Synonyms: GROS1,MGC117314,P3H1

ID gène: 64175