CHORDC1 anticorps (N-Term)
Aperçu rapide pour CHORDC1 anticorps (N-Term) (ABIN5514389)
Antigène
Voir toutes CHORDC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- TYHPGVPVFH DALKGWSCCK RRTTDFSDFL SIVGCTKGRH NSEKPPEPVK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against CHRD1. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRD1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))
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Autre désignation
- CHRD1
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Sujet
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CHRD1 regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. It is proposed to act as co-chaperone for HSP90. CHRD1 may play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, it has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. It is involved in stress response. It prevents tumorigenesis.
Alias Symbols: CHORDC1, CHP1,
Protein Interaction Partner: TARS2, XPO5, CDC37L1, CDC37, TOMM34, AHSA1, TUBA1B, TTC4, PPP5C, HSP90AB1, HSP90AA1, FKBP5, FKBP4, BCCIP, NAGK, C11orf58, SUGT1, KYNU, TCEA1, SORD, SMS, PGD, CSE1L, XPO1, UBC, PAK1, CHORDC1,
Protein Size: 332 -
ID gène
- 26973
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NCBI Accession
- NP_036256
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UniProt
- Q9UHD1
Antigène
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