CRBA1 anticorps (C-Term)

N° du produit ABIN5514391

L’anticorps Lapin Polyclonal anti-CRBA1 a été validé pour WB. Il convient pour détecter CRBA1 dans des échantillons de Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour CRBA1 anticorps (C-Term) (ABIN5514391)

Antigène: CRBA1 (beta-Crystallin a3 (CRBA1))

Reactivité: Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Détail du produit anti-CRBA1 anticorps

Épitope: C-Term

Séquence: SGAWVCYQYP GYRGYQYILE CDHHGGDYKH WREWGSHAQT SQIQSIRRIQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CRBA1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CRBA1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRBA1

Antigène: CRBA1 (beta-Crystallin a3 (CRBA1))

Autre désignation: CRBA1

Sujet: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'.

Alias Symbols: CRYBA1, CRYB1,

Protein Interaction Partner: RHOXF2, RBPMS, CRYBB3, CRYBB1, CRYBA1, CRYAB, CRYAA,

Protein Size: 215

ID gène: 1411

NCBI Accession: NP_005199

UniProt: P05813