Glucosylceramidase anticorps (N-Term)

N° du produit ABIN5514399

Cet anticorps Lapin Polyclonal détecte spécifiquement Glucosylceramidase dans WB. Il présente une réactivité envers Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin et Rat.

Aperçu rapide pour Glucosylceramidase anticorps (N-Term) (ABIN5514399)

Antigène: Glucosylceramidase (GLCM)

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glucosylceramidase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Glucosylceramidase anticorps

Épitope: N-Term

Séquence: FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS

Homologie: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%

Attributs du produit: This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Glucosylceramidase

Antigène: Glucosylceramidase (GLCM)

Autre désignation: GLCM

Sujet: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Alias Symbols: GBA, GC, GLUC,

Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,

Protein Size: 536

ID gène: 2629

NCBI Accession: XP_006711333

UniProt: P04062