Glucosylceramidase anticorps (N-Term)

N° du produit ABIN5514399

Détail du produit anti-Glucosylceramidase anticorps

Antigène: Glucosylceramidase (GLCM)

Épitope: N-Term

Reactivité: Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Porc, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Séquence: FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS

Homologie: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%

Attributs du produit: This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Glucosylceramidase

Antigène: Glucosylceramidase (GLCM)

Autre désignation: GLCM (GLCM Produits)

Sujet: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Alias Symbols: GBA, GC, GLUC,

Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,

Protein Size: 536

ID gène: 2629

NCBI Accession: XP_006711333

UniProt: P04062