MARCH8 anticorps (N-Term)
Aperçu rapide pour MARCH8 anticorps (N-Term) (ABIN5514406)
Antigène
Voir toutes MARCH8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- MARCH8 Antibody - N-terminal region
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Séquence
- MSMPLHQISA IPSQDAISAR VYRSKTKEKE REEQNEKTLG HFMSHSSNIS
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Attributs du produit
- This is a rabbit polyclonal antibody against MARH8. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MARH8
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75860-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))
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Autre désignation
- MARCH8
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Sujet
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Background Information: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153], Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]
Gene Name: membrane associated ring-CH-type finger 8
Alternative Symbols: MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII
Protein Name: E3 ubiquitin-protein ligase MARCH8
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Poids moléculaire
- 32kDa
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ID gène
- 220972
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UniProt
- Q5T0T0
Antigène
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