RITA1 anticorps (C-Term)
Aperçu rapide pour RITA1 anticorps (C-Term) (ABIN5514467)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- TNGPQDLRPS TSGVTFRSPL VTSRARSVSI SVPSTPRRGG ATQKPKPPWK
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Attributs du produit
- This is a rabbit polyclonal antibody against RITA1. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RITA1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))
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Autre désignation
- RITA1
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Sujet
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RITA1 is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.
Alias Symbols: C12orf52, RITA, PSEC0043
Protein Size: 269 -
ID gène
- 84934
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NCBI Accession
- XP_005254029
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UniProt
- Q96K30
Antigène
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