ANAPC5 anticorps (Middle Region)

N° du produit ABIN5514501

Détail du produit anti-ANAPC5 anticorps

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC5 est non-conjugé

Application: Western Blotting (WB)

Séquence: HSLLHYFDRL ILTGAESKSN GEEGYGRSLR YAALNLAALH CRFGHYTSPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ANAPC5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human ANAPC5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ANAPC5

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Autre désignation: ANAPC5 (ANAPC5 Produits)

Synonymes: anticorps APC5, anticorps DDBDRAFT_0206386, anticorps DDBDRAFT_0234269, anticorps DDB_0206386, anticorps DDB_0234269, anticorps zgc:55800, anticorps wu:fb75a09, anticorps ANAPC5, anticorps MGC89697, anticorps 2510006G12Rik, anticorps AA408751, anticorps AA536819, anticorps AA986414, anticorps Anpc5, anticorps F12K11.7, anticorps F12K11_7, anticorps anaphase promoting complex subunit 5, anticorps anaphase-promoting complex subunit 5, anticorps anaphase promoting complex subunit 5 L homeolog, anticorps anaphase-promoting complex subunit, anticorps anaphase-promoting complex subunit Apc5, anticorps ANAPC5, anticorps anapc5, anticorps LOC100093215, anticorps anapc5.L, anticorps Anapc5, anticorps AT1G06590, anticorps apc5

Sujet: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Alias Symbols: ANAPC5, APC5,

Protein Interaction Partner: ANAPC2, UBE2S, UBC, ANAPC4, HECW2, LATS2, PHF8, SOX2, PTEN, CDC27, BACH1, TRIM33, ANAPC7, ANAPC15, CDH1, CDC20, PAXIP1, MDC1, TP53BP1, NOTCH1, ANAPC1, ANAPC13, CDC16, CDC23, FBXO5, USP37, CUL4A, SH3KBP1, E2F1, SMARCAD1, MAPK6, Gm9174, Anapc5, Mad2l1, Anap

Protein Size: 219

ID gène: 51433

Pathways: M Phase