Cytohesin 2 anticorps (C-Term)

N° du produit ABIN5514510

Cet anticorps Lapin Polyclonal détecte spécifiquement Cytohesin 2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Mouton, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Cytohesin 2 anticorps (C-Term) (ABIN5514510)

Antigène: Cytohesin 2 (CYTH2)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Mouton, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytohesin 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cytohesin 2 anticorps

Épitope: C-Term

Séquence: GRVKTWKRRW FILTDNCLYY FEYTTDKEPR GIIPLENLSI REVDDPRKPN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CYTH2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYTH2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cytohesin 2

Antigène: Cytohesin 2 (CYTH2)

Autre désignation: CYTH2

Sujet: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83 % homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like

Protein Interaction Partner: CCDC120, UBC, ARF6, GNAQ, PNPLA2, DYT10, MAPK6, APC, IPCEF1, ATP6V0A2, CYTIP, ARFGAP1, TRIM23, ITGB2, PRKCG, PRKCB, PRKCA, CUX1, ARRB2, ARRB1, ARF1, ADORA2A, ARF3, SFN,

Protein Size: 400

ID gène: 9266

NCBI Accession: NM_017457, NP_059431

UniProt: Q99418