Neural Wiskott-Aldrich syndrome protein (WASL) (N-Term) anticorps
Aperçu rapide pour Neural Wiskott-Aldrich syndrome protein (WASL) (N-Term) anticorps (ABIN5514539)
Antigène
Voir toutes Neural Wiskott-Aldrich syndrome protein (WASL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- FANEEEAKKF RKAVTDLLGR RQRKSEKRRD PPNGPNLPMA TVDIKNPEIT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human WASL
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Neural Wiskott-Aldrich syndrome protein (WASL)
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Autre désignation
- WASL
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Sujet
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This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.
Alias Symbols: NWASP, WASPB, N-WASP
Protein Interaction Partner: RHOJ, ARPC3, RNF8, NCK2, WIPF1, SDCBP, PTK6, GRB2, IQGAP1, WWOX, SNX9, APBB1, PRPF40A, FNBP1L, FNBP1, TRIP10, PSTPIP1, ACTG1, SORBS3, ACTR2, ACTR3, LCK, CDC42, RPL7AP66, ZNF395, BAIAP2, ARPC1B, FCHSD2, IPO5, HP, HSP90AB1, HSP90AA1, SRC, WASF2, APP, WIPF2,
Protein Size: 505 -
ID gène
- 8976
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NCBI Accession
- NM_003941, NP_003932
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UniProt
- O00401
Antigène
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