Opiorphin Prepropeptide (OPRPN) (N-Term) anticorps

N° du produit ABIN5514594

Cet anticorps Lapin Polyclonal détecte spécifiquement Opiorphin Prepropeptide dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Opiorphin Prepropeptide (OPRPN) (N-Term) anticorps (ABIN5514594)

Antigène: Opiorphin Prepropeptide (OPRPN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Détail du produit

Épitope: N-Term

Fonction: OPRPN Antibody - N-terminal region

Séquence: SFNYTTPDYG HYDDKDTLDL NTPVDKTSNT LRVPDILALV IFAVVFLVGV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human C5AR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP77605-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Opiorphin Prepropeptide (OPRPN)

Autre désignation: OPRPN

Sujet:

Background Information: This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants.

Gene Name: opiorphin prepropeptide

Alternative Symbols: BPLP, PRL1, PROL1, opiorphin

Protein Name: opiorphin prepropeptide

Poids moléculaire: 38 kDa

ID gène: 58503

NCBI Accession: NP_001727

UniProt: P21730