CEP290 anticorps (N-Term)

N° du produit ABIN5514637

L’anticorps anti-CEP290 Polyclonal Lapin est utilisé pour la détection de CEP290 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CEP290 anticorps (N-Term) (ABIN5514637)

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEP290 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CEP290 anticorps

Épitope: N-Term

Fonction: CEP290 Antibody - N-terminal region

Séquence: EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CEP290

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80284-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CEP290

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Autre désignation: CEP290

Sujet:

Background Information: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

Gene Name: centrosomal protein 290 kDa

Alternative Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag

Protein Name: centrosomal protein of 290 kDa

Poids moléculaire: 88 kDa

ID gène: 80184

NCBI Accession: NP_079390

UniProt: Q05BJ6

Pathways: cAMP Metabolic Process, M Phase