AKR1C1 anticorps (C-Term)
Aperçu rapide pour AKR1C1 anticorps (C-Term) (ABIN5514650)
Antigène
Voir toutes AKR1C1 (DDH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LVAYSALGSH REEPWVDPNS PVLLEDPVLC ALAKKHKRTP ALIALRYQLQ
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Attributs du produit
- This is a rabbit polyclonal antibody against AK1C1. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human AK1C1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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Autre désignation
- AK1C1
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Sujet
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: AKR1C1, DDH, DDH1,
Protein Size: 323 -
ID gène
- 1645
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NCBI Accession
- NP_001344
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UniProt
- Q04828
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Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
Antigène
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