AKR1C1 anticorps (C-Term)

N° du produit ABIN5514650

Cet anticorps anti-AKR1C1 Polyclonal Lapin (ABIN5514650) détecte spécifiquement AKR1C1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AKR1C1 anticorps (C-Term) (ABIN5514650)

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AKR1C1 anticorps

Épitope: C-Term

Fonction: AKR1C1 Antibody - C-terminal region

Séquence: LVAYSALGSH REEPWVDPNS PVLLEDPVLC ALAKKHKRTP ALIALRYQLQ

Attributs du produit: This is a rabbit polyclonal antibody against AK1C1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AK1C1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76080-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1C1

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Autre désignation: AKR1C1

Sujet:

Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Gene Name: aldo-keto reductase family 1 member C1

Alternative Symbols: C9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD

Protein Name: aldo-keto reductase family 1 member C1

Poids moléculaire: 35kDa

ID gène: 1645

NCBI Accession: NP_001344

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process