DUOX1 anticorps (N-Term)

N° du produit ABIN5514730

L’anticorps anti-DUOX1 Polyclonal Lapin est utilisé pour la détection de DUOX1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour DUOX1 anticorps (N-Term) (ABIN5514730)

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUOX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUOX1 anticorps

Épitope: N-Term

Fonction: DUOX1 Antibody - N-terminal region

Séquence: LLVGAWTPLG AQNPISWEVQ RFDGWYNNLM EHRWGSKGSR LQRLVPASYA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DUOX1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80953-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DUOX1

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Autre désignation: DUOX1

Sujet:

Background Information: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene Name: dual oxidase 1

Alternative Symbols: LNOX1, THOX1, NOXEF1

Protein Name: dual oxidase 1

Poids moléculaire: 170 kDa

ID gène: 53905

NCBI Accession: NP_059130

UniProt: Q9NRD9