RPS19 anticorps (C-Term)

N° du produit ABIN5514788

Cet anticorps anti-RPS19 Polyclonal Lapin (ABIN5514788) détecte spécifiquement RPS19 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RPS19 anticorps (C-Term) (ABIN5514788)

Antigène: RPS19 (Ribosomal Protein S19 (RPS19))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS19 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RPS19 anticorps

Épitope: C-Term

Séquence: SKSVARRVLQ ALEGLKMVEK DQDGGRKLTP QGQRDLDRIA GQVAAANKKH

Attributs du produit: This is a rabbit polyclonal antibody against RS19. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RS19

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RPS19

Antigène: RPS19 (Ribosomal Protein S19 (RPS19))

Autre désignation: RS19

Sujet: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Alias Symbols: RPS19,

Protein Interaction Partner: TP53, HUWE1, CEP250, NEDD1, TUBGCP4, TUBGCP2, PPP2R1A, AURKA, UBC, MDM2, RPS17, RNF2, WIBG, EIF2A, TSR1, SERBP1, EIF3E, FAU, RPS29, RPS28, RPS26, RPS25, RPS24, RPS23, RPS20, RPS18, RPS16, RPS15A, RPS15, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6,

Protein Size: 145

ID gène: 6223

NCBI Accession: NP_001013

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly