TDO2 anticorps (C-Term)
Aperçu rapide pour TDO2 anticorps (C-Term) (ABIN5514793)
Antigène
Voir toutes TDO2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- TDO2 Antibody - C-terminal region
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Séquence
- MDIDSLMTKW RYNHVCMVHR MLGSKAGTGG SSGYHYLRST VSDRYKVFVD
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against T23O. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human T23O
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45718-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
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Autre désignation
- TDO2
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Sujet
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Background Information: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.
Gene Name: tryptophan 2,3-dioxygenase
Alternative Symbols: TO, TDO, TPH2, TRPO, HYPTRP
Protein Name: tryptophan 2,3-dioxygenase
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Poids moléculaire
- 44kDa
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ID gène
- 6999
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NCBI Accession
- NP_005642
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UniProt
- P48775
Antigène
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