GRM2 anticorps (C-Term)

N° du produit ABIN5514828

Cet anticorps Lapin Polyclonal détecte spécifiquement GRM2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cobaye et Cheval.

Aperçu rapide pour GRM2 anticorps (C-Term) (ABIN5514828)

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRM2 anticorps

Épitope: C-Term

Séquence: AWLVVEAPGT GKETAPERRE VVTLRCNHRD ASMLGSLAYN VLLIALCTLY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GRM2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GRM2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRM2

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Autre désignation: GRM2

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: GPRC1B, MGLUR2

Protein Interaction Partner: NAALADL2, UBQLN1, GRASP, RGS12, GNAQ, GNA15, SMARCC2, SMARCA4, REST,

Protein Size: 872

ID gène: 2912

NCBI Accession: XP_006713184

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport