KLC1 anticorps (C-Term)

N° du produit ABIN5514913

L’anticorps Lapin Polyclonal anti-KLC1 a été validé pour WB. Il convient pour détecter KLC1 dans des échantillons de Humain.

Aperçu rapide pour KLC1 anticorps (C-Term) (ABIN5514913)

Antigène: KLC1 (Kinesin Light Chain 1 (KLC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KLC1 anticorps

Épitope: C-Term

Séquence: ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human KLC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KLC1

Antigène: KLC1 (Kinesin Light Chain 1 (KLC1))

Autre désignation: KLC1

Sujet: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

Alias Symbols: KLC, KNS2, KNS2A,

Protein Interaction Partner: CCDC114, KRT31, BNIP2, UBC, EZH2, TLE3, KIF5B, DIAPH1, COPB1, ARCN1, KLC4, KLC2, SMEK2, PTPN23, COPZ1, APP, RIC3, BSDC1, FAM63B, PRKAG3, LDLRAP1, RASSF8, YWHAE, SKP1, SNCA, KIF5A, MAPK6, YWHAB, LRSAM1, MAPK8IP3, PLEKHM2, CLSTN1, SPAG9, MAPK8IP2, MAPK8IP1,

Protein Size: 551

ID gène: 3831

NCBI Accession: NM_001130107, NP_005543

Pathways: Ribonucleoprotein Complex Subunit Organization