MDFI anticorps (Middle Region)
Aperçu rapide pour MDFI anticorps (Middle Region) (ABIN5514974)
Antigène
Voir toutes MDFI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- MDFI Antibody - middle region
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Séquence
- AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
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Homologie
- Cow: 79%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Sheep: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against MDFI. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human MDFI
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50514-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MDFI (MyoD Family Inhibitor (MDFI))
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Autre désignation
- MDFI
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Sujet
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Background Information: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Gene Name: MyoD family inhibitor
Alternative Symbols: I-MF, I-mfa
Protein Name: MyoD family inhibitor
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Poids moléculaire
- 27kDa
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ID gène
- 4188
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NCBI Accession
- NP_005577
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UniProt
- Q99750
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Pathways
- Maintenance of Protein Location
Antigène
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