MDFI anticorps (Middle Region)

N° du produit ABIN5514974

Détail du produit anti-MDFI anticorps

Antigène: MDFI (MyoD Family Inhibitor (MDFI))

Épitope: Middle Region

Reactivité: Humain, Lapin, Mouton, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDFI est non-conjugé

Application: Western Blotting (WB)

Séquence: AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH

Homologie: Cow: 79%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MDFI. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human MDFI

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MDFI

Antigène: MDFI (MyoD Family Inhibitor (MDFI))

Autre désignation: MDFI (MDFI Produits)

Synonymes: anticorps MDFI, anticorps I-MF, anticorps I-mfa, anticorps I-mf, anticorps RGD1560271, anticorps MyoD family inhibitor, anticorps MDFI, anticorps Mdfi

Sujet: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Alias Symbols: MDFI,

Protein Interaction Partner: PDIA5, USP20, ARID5A, ZNF266, KAT5, SPRY2, SPRY1, NR1H3, ZBTB24, ARHGAP32, KIAA0040, CREB5, MAGED1, ZNF264, GTF3C5, APLN, AKAP17A, ZNF230, ZNF223, ZNF155, ZNF138, ZNF136, ZNF124, ZNF79, WNT11, VHL, NR1H2, TYRO3, TNP2, TNNI1, TGIF1, GNAI2, GATA2, EIF4A2, D

Protein Size: 246

ID gène: 4188

NCBI Accession: NP_005577

UniProt: Q99750

Pathways: Maintenance of Protein Location