UBTF anticorps (C-Term)

N° du produit ABIN5515000

L’anticorps Lapin Polyclonal anti-UBTF a été validé pour WB. Il convient pour détecter UBTF dans des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Porc, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).

Aperçu rapide pour UBTF anticorps (C-Term) (ABIN5515000)

Antigène: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Porc, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBTF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBTF anticorps

Épitope: C-Term

Séquence: SEDGGDSSES SSEDESEDGD ENEEDDEDED DDEDDDEDED NESEGSSSSS

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 93%, Yeast: 86%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against UBF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBTF

Antigène: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Autre désignation: UBF1

Sujet: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Alias Symbols: UBTF, UBF, UBF1,

Protein Interaction Partner: UBC, MDM2, RNF2, Dlg4, ESR1, CDK4, CDK2, CCNE1, CCND1, WDR70, YEATS4, RB1, GRK5, KAT5, SIRT7, POLR1A, MYBBP1A, HDAC1, RUNX2, SUMO2, SMARCA5, MAPK3, MAPK1, SUMO1, PIK3CA, IRS1, TAF1D, tat, MCRS1, TLE1, ACTN4, POLR1E, CHGB, SMURF1, TCOF1, MAD1L1, ZMYM2, SER

Protein Size: 764

ID gène: 7343

NCBI Accession: XP_006722124

UniProt: P17480