PTPMT1 anticorps (N-Term)

N° du produit ABIN5515057

L’anticorps anti-PTPMT1 Polyclonal Lapin est utilisé pour la détection de PTPMT1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour PTPMT1 anticorps (N-Term) (ABIN5515057)

Antigène: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPMT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PTPMT1 anticorps

Épitope: N-Term

Fonction: PTPMT1 Antibody - N-terminal region

Séquence: LFYPTLLYTL FRGKVPGRAH RDWYHRIDPT VLLGALPLRS LTRQLVQDEN

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PTPMT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79956-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTPMT1

Antigène: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Autre désignation: PTPMT1

Sujet:

Background Information: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity).

Gene Name: protein tyrosine phosphatase, mitochondrial 1

Alternative Symbols: MOSP, PLIP, DUSP23, PNAS-129

Protein Name: phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

Poids moléculaire: 23 kDa

ID gène: 114971

NCBI Accession: NP_001137456

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process