RASA3 anticorps (N-Term)

N° du produit ABIN5515101

Cet anticorps Lapin Polyclonal détecte spécifiquement RASA3 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RASA3 anticorps (N-Term) (ABIN5515101)

Antigène: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASA3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RASA3 anticorps

Épitope: N-Term

Fonction: RASA3 Antibody - N-terminal region

Séquence: YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL

Attributs du produit: This is a rabbit polyclonal antibody against RASA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74174-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RASA3

Antigène: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Autre désignation: RASA3

Sujet:

Background Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Alternative Symbols: GAPIII, GAP1IP4BP

Poids moléculaire: 91kDa

ID gène: 22821

NCBI Accession: NP_031394

UniProt: Q14644