ARHGDIB anticorps (N-Term)
Aperçu rapide pour ARHGDIB anticorps (N-Term) (ABIN5515373)
Antigène
Voir toutes ARHGDIB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against ARHGDIB. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGDIB
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
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Autre désignation
- ARHGDIB
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Sujet
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Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.
Alias Symbols: D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2
Protein Interaction Partner: ZBTB1, Rabgef1, Rab6a, APP, UBC, UFM1, RAC3, RAC1, RAC2, RHOH, CASP3, RHOA, VAV1, EZR, CDC42, CUL3, KLHL12,
Protein Size: 201 -
ID gène
- 397
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NCBI Accession
- NM_001175, NP_001166
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UniProt
- P52566
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Pathways
- Caspase Cascade in Apoptosis
Antigène
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