CCAR1 anticorps (C-Term)

N° du produit ABIN5515401

Cet anticorps Lapin Polyclonal détecte spécifiquement CCAR1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Porc et Cobaye.

Aperçu rapide pour CCAR1 anticorps (C-Term) (ABIN5515401)

Antigène: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Porc, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCAR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCAR1 anticorps

Épitope: C-Term

Séquence: YDPMEAEEAE DEEDDRDEEE MTKRDDKRDI NRYCKERPSK DKEKEKTQMI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CCAR1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCAR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCAR1

Antigène: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Autre désignation: CCAR1

Sujet: CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. It is recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. It also functions as a p53 coactivator. It may thus play an important role in transcriptional regulation (By similarity). It may be involved in apoptosis signaling in the presence of the reinoid CD437. It apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. And it plays a role in cell cycle progression and/or cell proliferation.

Alias Symbols: CARP1, DIS

Protein Interaction Partner: PIH1D3, GOLGA2, SUMO2, SUMO3, UBC, TP53, MDM2, U2AF2, CHERP, UBL4A, RBM10, RNF113A, HNRNPK, SMURF1, BARD1, SIRT7, SF3A2, Kif23, FYCO1, CASP10, SFN, YWHAQ,

Protein Size: 1150

ID gène: 55749

NCBI Accession: NP_060707

UniProt: Q8IX12