CCM2 anticorps (N-Term)

N° du produit ABIN5515477

L’anticorps Lapin Polyclonal anti-CCM2 a été validé pour WB. Il convient pour détecter CCM2 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour CCM2 anticorps (N-Term) (ABIN5515477)

Antigène: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCM2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCM2 anticorps

Épitope: N-Term

Séquence: EFHTGYSMEN EPGIVSPFKR VFLKGEKSRD KKAHEKVTER RPLHTVVLSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CCM2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CCM2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCM2

Antigène: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Autre désignation: CCM2

Sujet: This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: C7orf22, PP10187

Protein Interaction Partner: SRPK2, SMURF2, SMURF1, POT1,

Protein Size: 465

ID gène: 83605

Pathways: Cell-Cell Junction Organization