ALDOB anticorps (N-Term)
Aperçu rapide pour ALDOB anticorps (N-Term) (ABIN5515769)
Antigène
Voir toutes ALDOB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- ADESVGTMGN RLQRIKVENT EENRRQFREI LFSVDSSINQ SIGGVILFHE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 90%, Zebrafish: 75%
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Attributs du produit
- This is a rabbit polyclonal antibody against ALDOB. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ALDOB
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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Autre désignation
- ALDOB
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Sujet
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Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
Alias Symbols: ALDOB, ALDB,
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, MUC20, AGXT2, TXN2, UBC, HIVEP1, ALDOA, APP, HSPA8, ALDOB, ATP6V1E1,
Protein Size: 364 -
ID gène
- 229
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NCBI Accession
- NP_000026
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UniProt
- P05062
Antigène
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