AIPL1 anticorps (C-Term)

N° du produit ABIN5515809

Cet anticorps Lapin Polyclonal détecte spécifiquement AIPL1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc et Lapin.

Aperçu rapide pour AIPL1 anticorps (C-Term) (ABIN5515809)

Antigène: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIPL1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AIPL1 anticorps

Épitope: C-Term

Fonction: AIPL1 Antibody - C-terminal region

Séquence: DLDELQKEPQ PLVFVIELLQ VDAPSDYQRE TWNLSNHEKM KAVPVLHGEG

Homologie: Cow: 79%, Horse: 86%, Human: 100%, Mouse: 77%, Pig: 86%, Rabbit: 79%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against AIPL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human AIPL1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72738-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur AIPL1

Antigène: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Autre désignation: AIPL1

Sujet:

Background Information: Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5 % of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20 % of recessive LCA. Alternative splicing results in multiple transcript variants.

Gene Name: aryl hydrocarbon receptor interacting protein-like 1

Alternative Symbols: LCA4, AIPL2

Protein Name: aryl-hydrocarbon-interacting protein-like 1

Poids moléculaire: 29kDa

ID gène: 23746

NCBI Accession: NP_001272332

UniProt: F1T0C4