IKAP/p150 anticorps (C-Term)

N° du produit ABIN5516011

L’anticorps anti-IKAP/p150 Polyclonal Lapin est utilisé pour la détection de IKAP/p150 dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval et Lapin. Il a été validé pour WB.

Aperçu rapide pour IKAP/p150 anticorps (C-Term) (ABIN5516011)

Antigène: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKAP/p150 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IKAP/p150 anticorps

Épitope: C-Term

Séquence: SRISARSSKN RRKAERKKHS LKEGSPLEDL ALLEALSEVV QNTENLKDEV

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IKBKAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human IKBKAP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IKAP/p150

Antigène: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Autre désignation: IKBKAP

Sujet: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alias Symbols: FD, DYS, ELP1, IKAP, IKI3, TOT1

Protein Size: 346

ID gène: 8518

NCBI Accession: NM_003640, NP_003631

UniProt: O95163