GAMT anticorps (N-Term)

N° du produit ABIN5516042

Cet anticorps anti-GAMT Polyclonal Lapin (ABIN5516042) détecte spécifiquement GAMT dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Poisson zèbre (Danio rerio), Cobaye, Boeuf (Vache), Chien et Cheval.

Aperçu rapide pour GAMT anticorps (N-Term) (ABIN5516042)

Antigène: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GAMT anticorps

Épitope: N-Term

Fonction: GAMT Antibody - N-terminal region

Séquence: IPLKGLWEDV APTLPDGHFD GILYDTYPLS EETWHTHQFN FIKNHAFRLL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against GAMT. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GAMT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41685-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GAMT

Antigène: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Autre désignation: GAMT

Sujet:

Background Information: The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Gene Name: guanidinoacetate N-methyltransferase

Alternative Symbols: PIG2, CCDS2, TP53I2, HEL-S-20

Protein Name: Guanidinoacetate N-methyltransferase

Poids moléculaire: 29kDa

ID gène: 2593

NCBI Accession: NP_620279

UniProt: Q14353