LITAF anticorps (N-Term)

N° du produit ABIN5516083

Détail du produit anti-LITAF anticorps

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LITAF est non-conjugé

Application: Western Blotting (WB)

Séquence: PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN

Attributs du produit: This is a rabbit polyclonal antibody against LITAF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LITAF

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LITAF

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Autre désignation: LITAF (LITAF Produits)

Synonymes: anticorps PIG7, anticorps SIMPLE, anticorps TP53I7, anticorps EET-1, anticorps Pig7, anticorps TNF-alpha, anticorps 3222402J11Rik, anticorps C85531, anticorps N4WBP3, anticorps TBX1, anticorps lipopolysaccharide induced TNF factor, anticorps lipopolysaccharide-induced TNF factor, anticorps LPS-induced TN factor, anticorps LITAF, anticorps Litaf

Sujet: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Alias Symbols: LITAF, PIG7, SIMPLE,

Protein Interaction Partner: REEP6, UBQLN1, STAM2, CALCOCO2, BAG3, HGS, UBC, STAT6, ATXN1, ITCH, TSG101, NEDD4, ELAVL1, RADIL, SMAD2, COMT,

Protein Size: 228

ID gène: 9516

Pathways: Cellular Response to Molecule of Bacterial Origin