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Urm1 anticorps (N-Term)

Urm1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5516189
  • Antigène Voir toutes Urm1 Anticorps
    Urm1 (Ubiquitin Related Modifier 1 (Urm1))
    Épitope
    • 7
    • 7
    • 1
    • 1
    N-Term
    Reactivité
    • 27
    • 10
    • 10
    • 1
    Humain
    Hôte
    • 27
    • 2
    Lapin
    Clonalité
    • 27
    • 2
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Urm1 est non-conjugé
    Application
    • 21
    • 17
    • 11
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    TLPGQEEPWD IRNLLIWIKK NLLKERPELF IQGDSVRPGI LVLINDADWE
    Attributs du produit
    This is a rabbit polyclonal antibody against URM1. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human URM1
    Top Product
    Discover our top product Urm1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Urm1 (Ubiquitin Related Modifier 1 (Urm1))
    Autre désignation
    URM1 (Urm1 Produits)
    Synonymes
    anticorps RGD1306599, anticorps C9orf74, anticorps 2900073H19Rik, anticorps ubiquitin related modifier 1, anticorps ubiquitin related modifier, anticorps ubiquitin-related modifier, anticorps Ubiquitin-related modifier 1 homolog, anticorps Urm1, anticorps LOC733109, anticorps URM1
    Sujet
    URM1 acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). URM1 serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

    Alias Symbols: C9orf74

    Protein Interaction Partner: SEC23IP, DSTN, PTGES3, TXNL1, USP5, XPO1, VCL, PRDX2, PRDX1, ATP6V1A, CTU1, UBC, ASCC2, TBL3, CDK11B, UBA4,

    Protein Size: 101
    ID gène
    81605
    NCBI Accession
    NP_112176
    UniProt
    Q9BTM9
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