CRBN anticorps (Middle Region)

N° du produit ABIN5516299

L’anticorps Lapin Polyclonal anti-CRBN a été validé pour WB. Il convient pour détecter CRBN dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Chien.

Aperçu rapide pour CRBN anticorps (Middle Region) (ABIN5516299)

Antigène: CRBN (Cereblon (CRBN))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRBN est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRBN anticorps

Épitope: Middle Region

Séquence: GIEIVKVKAI GRQRFKVLEL RTQSDGIQQA KVQILPECVL PSTMSAVQLE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CRBN. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human CRBN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRBN

Antigène: CRBN (Cereblon (CRBN))

Autre désignation: CRBN

Sujet: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: CRBN, AD-006,

Protein Interaction Partner: PAK7, RBPMS, MEIS2, DDB1, IKZF3, IKZF1, SUV39H1, KDM1A, UBC, COPS4, COPS6, COPS3, PSMB4, PSMA2, COPS5, CUL4A, PRKAA1, RBX1,

Protein Size: 442

ID gène: 51185

NCBI Accession: NP_057386

UniProt: Q96SW2