DPM2 anticorps (Middle Region)

N° du produit ABIN5516306

Détail du produit anti-DPM2 anticorps

Antigène: DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPM2 est non-conjugé

Application: Western Blotting (WB)

Séquence: DSQHVIHKYF LPRAYAVAIP LAAGLLLLLF VGLFISYVML KTKRVTKKAQ

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DPM2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DPM2

Antigène: DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))

Autre désignation: DPM2 (DPM2 Produits)

Synonymes: anticorps dpm2b, anticorps dpm2a, anticorps AW557993, anticorps R75484, anticorps CDG1U, anticorps wu:fa99c01, anticorps zgc:112514, anticorps dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog, anticorps dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit L homeolog, anticorps dolichol-phosphate (beta-D) mannosyltransferase 2, anticorps dolichyl-phosphate mannosyltransferase subunit 2, regulatory, anticorps dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit, anticorps dpm2.S, anticorps dpm2.L, anticorps Dpm2, anticorps DPM2, anticorps dpm2

Sujet: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.

Alias Symbols: CDG1U

Protein Size: 84

ID gène: 8818

NCBI Accession: NM_003863, NP_003854

UniProt: O94777

Pathways: Inositol Metabolic Process