Chitotriosidase 1 anticorps (C-Term)

N° du produit ABIN5516322

Cet anticorps Lapin Polyclonal détecte spécifiquement Chitotriosidase 1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Chitotriosidase 1 anticorps (C-Term) (ABIN5516322)

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chitotriosidase 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Chitotriosidase 1 anticorps

Épitope: C-Term

Fonction: CHIT1 Antibody - C-terminal region

Séquence: GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CHIT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81460-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Chitotriosidase 1

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Autre désignation: CHIT1

Sujet:

Background Information: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Gene Name: chitinase 1

Alternative Symbols: CHI3, CHIT, CHITD

Protein Name: chitotriosidase-1

Poids moléculaire: 51 kDa

ID gène: 1118

NCBI Accession: NP_001243054

UniProt: Q13231