Chitotriosidase 1 anticorps (C-Term)

N° du produit ABIN5516322

Détail du produit anti-Chitotriosidase 1 anticorps

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chitotriosidase 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CHIT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Chitotriosidase 1

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Autre désignation: CHIT1 (CHIT1 Produits)

Synonymes: anticorps CHI3, anticorps CHIT, anticorps CHITD, anticorps CHIT1, anticorps chio, anticorps 2300002L19Rik, anticorps chitinase 1, anticorps chitinase 1 (chitotriosidase), anticorps CHIT1, anticorps chit1, anticorps Chit1

Sujet: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Alias Symbols: CHI3, CHIT, CHITD

Protein Size: 466

ID gène: 1118

NCBI Accession: NM_001256125, NP_001243054

UniProt: Q13231