Cet anticorps Lapin Polyclonal détecte spécifiquement HERV-FRD Provirus Ancestral Env Polyprotein dans WB. Il présente une réactivité avec des échantillons de Humain.
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Alias Symbols: ERVFRD-1, ERVFRDE1, UNQ6191/PRO20218,