HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (C-Term) anticorps

N° du produit ABIN5516370

Détail du produit

Antigène: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Séquence: PLVSLLLLLL FGPCLLNLIT QFVSSRLQAI KLQTNLSAGR HPRNIQESPF

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ERVFRD-1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ERVFRD-1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Autre désignation: ERVFRD-1 (Herv-frd Produits)

Synonymes: anticorps ERVFRDE1, anticorps GLLL6191, anticorps HERV-FRD, anticorps HERV-W/FRD, anticorps UNQ6191, anticorps envFRD, anticorps Gm52, anticorps Syna, anticorps endogenous retrovirus group FRD member 1, envelope, anticorps ERVFRD-1, anticorps Ervfrd-1

Classe de substances: Viral Protein

Sujet: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Alias Symbols: ERVFRD-1, ERVFRDE1, UNQ6191/PRO20218,

Protein Interaction Partner: APP,

Protein Size: 538

ID gène: 405754

NCBI Accession: NP_997465

UniProt: P60508