CD1c anticorps (C-Term)
Aperçu rapide pour CD1c anticorps (C-Term) (ABIN5516504)
Antigène
Voir toutes CD1c (CD1C) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- ASGFYPKPVW VTWMRNEQEQ LGTKHGDILP NADGTWYLQV ILEVASEEPA
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Homologie
- Human: 100%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against CD1C. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1C
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
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Autre désignation
- CD1C
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Sujet
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This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Alias Symbols: BDCA1, CD1, CD1A, R7
Protein Size: 333 -
ID gène
- 911
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NCBI Accession
- NM_001765, NP_001756
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UniProt
- P29017
Antigène
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