CD1c anticorps (C-Term)

N° du produit ABIN5516504

Cet anticorps anti-CD1c Polyclonal Lapin (ABIN5516504) détecte spécifiquement CD1c dans WB. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour CD1c anticorps (C-Term) (ABIN5516504)

Antigène: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD1c est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD1c anticorps

Épitope: C-Term

Fonction: CD1C Antibody - C-terminal region

Séquence: ASGFYPKPVW VTWMRNEQEQ LGTKHGDILP NADGTWYLQV ILEVASEEPA

Homologie: Human: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CD1C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1C

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63373-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD1c

Antigène: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Autre désignation: CD1C

Sujet:

Background Information: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Alternative Symbols: R7, CD1, CD1A, BDCA1

Protein Name: T-cell surface glycoprotein CD1c

Poids moléculaire: 35kDa

ID gène: 911

NCBI Accession: NP_001756

UniProt: P29017