SLC16A2/MCT8 anticorps (N-Term)

N° du produit ABIN5516550

Cet anticorps Lapin Polyclonal détecte spécifiquement SLC16A2/MCT8 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SLC16A2/MCT8 anticorps (N-Term) (ABIN5516550)

Antigène: SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC16A2/MCT8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SLC16A2/MCT8 anticorps

Épitope: N-Term

Fonction: SLC16A2 Antibody - N-terminal region

Séquence: EPEPVPVPPP EPQPEPQPLP DPAPLPELEF ESERVHEPEP TPTVETRGTA

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC16A2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80952-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SLC16A2/MCT8

Antigène: SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))

Autre désignation: SLC16A2

Sujet:

Background Information: This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome.

Gene Name: solute carrier family 16, member 2 (thyroid hormone transporter)

Alternative Symbols: AHDS, MCT7, MCT8, XPCT, MCT 7, MCT 8, MRX22, DXS128, DXS128E

Protein Name: monocarboxylate transporter 8

Poids moléculaire: 59 kDa

ID gène: 6567

NCBI Accession: NP_006508

UniProt: P36021

Pathways: Hormone Transport