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KRIT1 anticorps (C-Term)
KRIT1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5516696
Détail du produit anti-KRIT1 anticorps
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Antigène
Voir toutes KRIT1 Anticorps
KRIT1
(KRIT1, Ankyrin Repeat Containing (KRIT1))
Épitope
Tous les épitopes à travers KRIT1 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur KRIT1 Anticorps
Humain
Hôte
Toutes les hôtes sur KRIT1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur KRIT1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers KRIT1 Anticorps
Cet anticorp KRIT1 est non-conjugé
Application
Tous les applications à travers KRIT1 Anticorps.
Western Blotting (WB)
Séquence
LLQIVYGNYE SKKHKQGFLN EENLKSIVPV TKLKSKAPHW TNRILHEYKN
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the C terminal region of human KRIT1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur KRIT1
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Antigène
KRIT1
(KRIT1, Ankyrin Repeat Containing (KRIT1))
Autre désignation
KRIT1 (KRIT1 Produits )
Synonymes
anticorps CAM, anticorps CCM1, anticorps 2010007K12Rik, anticorps A630036P20Rik, anticorps AA432855, anticorps AI450393, anticorps AI643869, anticorps BB155247, anticorps BB235701, anticorps Ccm1, anticorps RGD1305929, anticorps krit1, anticorps fb36f07, anticorps san, anticorps santa, anticorps wu:fb36f07, anticorps zgc:63585, anticorps KRIT1, ankyrin repeat containing, anticorps KRIT1, anticorps Krit1, anticorps krit1
Sujet
This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. Alias Symbols: CAM, CCM1 Protein Size: 529
ID gène
889
NCBI Accession
NM_001013406
Pathways
Cell RedoxHomeostasis
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