EIF5A anticorps (N-Term)

N° du produit ABIN5516707

L’anticorps anti-EIF5A Polyclonal Lapin est utilisé pour la détection de EIF5A dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour EIF5A anticorps (N-Term) (ABIN5516707)

Antigène: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF5A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EIF5A anticorps

Épitope: N-Term

Séquence: LKGRPCKIVE MSTSKTGKHG HAKVHLVGID IFTGKKYEDI CPSTHNMDVP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against EIF5A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human EIF5A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EIF5A

Antigène: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Autre désignation: EIF5A

Sujet: EIF5A is a mRNA-binding protein involved in translation elongation. It has an important function at the level of mRNA turnover, probably acting downstream of decapping. It is involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, EIF5A functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. EIF5A regulates also TNF-alpha-mediated apoptosis and mediates effects of polyamines on neuronal process extension and survival. It may play an important role in brain development and function, and in skeletal muscle stem cell differentiation. EIF5A is also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Protein Interaction Partner: HUWE1, UBC, REL, MEOX2, DHPS, CRX, DCP2, STUB1, BCCIP, WDR1, GDA, TYMS, PEPD, MVD, HSPD1, GNS, GLS, UBD, NPM1, IQCB1, ATF2, VCP, MACF1, DDX17, VAPA, XPO1, ATP5B, XPO4, CUL2, COPS5, TCF3, ELAVL1, SUMO2, VHL, Pds5a, Csnk1e, DOHH, XRN2, RPL5, TGM2,

Protein Size: 184

ID gène: 1984

Pathways: Regulation of Muscle Cell Differentiation