GLRB anticorps (N-Term)

N° du produit ABIN5516877

Cet anticorps Lapin Polyclonal détecte spécifiquement GLRB dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Lapin, Cobaye et Cheval.

Aperçu rapide pour GLRB anticorps (N-Term) (ABIN5516877)

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLRB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GLRB anticorps

Épitope: N-Term

Fonction: GLRB Antibody - N-terminal region

Séquence: LLTTAFLILI SLWVEEAYSK EKSSKKGKGK KKQYLCPSQQ SAEDLARVPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GLRB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLRB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34996-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GLRB

Antigène: GLRB (Glycine Receptor, beta (GLRB))

Autre désignation: GLRB

Sujet:

Background Information: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Gene Name: glycine receptor, beta

Alternative Symbols: HKPX2

Protein Name: Glycine receptor subunit beta

Poids moléculaire: 54kDa

ID gène: 2743

UniProt: P48167