FBXL15 anticorps (N-Term)

N° du produit ABIN5517039

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXL15 dans WB. Il présente une réactivité envers Humain, Boeuf (Vache), Chien, Chévre, Cheval, Souris, Lapin et Rat.

Aperçu rapide pour FBXL15 anticorps (N-Term) (ABIN5517039)

Antigène: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Reactivité: Humain, Boeuf (Vache), Chien, Chévre, Cheval, Souris, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXL15 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXL15 anticorps

Épitope: N-Term

Séquence: PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXL15

Antigène: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Autre désignation: FBXL15

Sujet: FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

Alias Symbols: FBXO37, Fbl15, JET, PSD

Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

Protein Size: 300

ID gène: 79176

NCBI Accession: NM_024326, NP_077302

UniProt: Q9H469