COQ6 anticorps (N-Term)

N° du produit ABIN5517062

Cet anticorps anti-COQ6 Polyclonal Lapin (ABIN5517062) détecte spécifiquement COQ6 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval et Saccharomyces cerevisiae.

Aperçu rapide pour COQ6 anticorps (N-Term) (ABIN5517062)

Antigène: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COQ6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COQ6 anticorps

Épitope: N-Term

Fonction: COQ6 Antibody - N-terminal region

Séquence: ILLLEAGPKK VLEKLSETYS NRVSSISPGS ATLLSSFGAW DHICNMRYRA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 80%

Attributs du produit: This is a rabbit polyclonal antibody against COQ6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64161-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur COQ6

Antigène: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Autre désignation: COQ6

Sujet:

Background Information: The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative Symbols: CGI10, CGI-10, COQ10D6

Protein Name: Ubiquinone biosynthesis monooxygenase COQ6

Poids moléculaire: 48kDa

ID gène: 51004

NCBI Accession: NP_872286

UniProt: Q9Y2Z9