MBNL2 anticorps (N-Term)

N° du produit ABIN5517157

L’anticorps anti-MBNL2 Polyclonal Lapin est utilisé pour la détection de MBNL2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MBNL2 anticorps (N-Term) (ABIN5517157)

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MBNL2 anticorps

Épitope: N-Term

Fonction: MBNL2 Antibody - N-terminal region

Séquence: CRQFQRGTCS RSDEECKFAH PPKSCQVENG RVIACFDSLK GRCSRENCKY

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MBNL2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74636-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MBNL2

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Autre désignation: MBNL2

Sujet:

Background Information: This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.

Gene Name: muscleblind like splicing regulator 2

Alternative Symbols: MBLL, MBLL39, PRO2032

Protein Name: muscleblind-like protein 2

Poids moléculaire: 40 kDa

ID gène: 10150

NCBI Accession: NP_001292999

UniProt: Q5VZF2