PHC3 anticorps (C-Term)
Aperçu rapide pour PHC3 anticorps (C-Term) (ABIN5517248)
Antigène
Voir toutes PHC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LSRWNRKPDN QSLGHRGRRP SGPDGAAREH ILRQLPITYP SAEEDLASHE
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Attributs du produit
- This is a rabbit polyclonal antibody against PHC3. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PHC3 (Polyhomeotic Homolog 3 (PHC3))
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Autre désignation
- PHC3
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Sujet
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PHC3 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: PHC3, EDR3, PH3,
Protein Interaction Partner: OGT, UBC, EED, RNF2, BMI1, SOX2, ALB, CBX2, PHC3, CBX8, CBX6, SCMH1, CBX4, PCGF2, SCML1, RING1, PHC2, PHC1, SUMO2,
Protein Size: 983 -
ID gène
- 80012
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NCBI Accession
- XP_005247847
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UniProt
- Q8NDX5
Antigène
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